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Mifepristone-induced abortion in one horn and a growing fetus in another horn in a patient with a twin pregnancy in a bicornuate uterus.

Chao A, Chao AS, Wang ST, Wang TH

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.

OBJECTIVE: To report a case of mifepristone-induced abortion in only one horn but a growing fetus in another horn for a twin pregnancy in a bicornuate uterus. DESIGN: Case report. SETTING: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taiwan. PATIENT(S): A 31-year-old woman who conceived spontaneously presented with 37 days' gestation. INTERVENTION(S): Mifepristone 600 mg orally followed by misoprostol 400 mug orally 2 days later. MAIN OUTCOME MEASURE(S): Termination of pregnancy. RESULT(S): Induced abortion in only one horn but a growing fetus in another horn for a twin pregnancy in the bicornuate uterus detected by ultrasound. Surgical abortion with vacuum curettage was performed, and menstruation resumed 1 month later. CONCLUSION(S): As medical abortion with mifepristone and misoprostol becomes more prevalent, more studies are necessary to establish the dosage and regimens for multiple pregnancies associated with uterine anomalies.

Published 27 November 2006 in Fertil Steril, 86(6): 1764.e3-5.
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